Staff Scientist

The Immunology Section, Liver Diseases Branch (NIDDK) is seeking an experienced scientist to study the role of wild-derived microbiota in preclinical mouse models of inflammation and metabolism. The candidate must have demonstrated experience in preclinical research with mice, and specifically in the management and husbandry of mouse colonies with wild-derived microbiota. The candidate must have at least 8-years experience in basic immunology, flow cytometry and molecular biology research, as well as data analysis skills. The Staff Scientist will divide time between conducting research projects in the laboratory and the management of the mouse colonies with wild-derived microbiota. The Staff Scientist will conduct mechanistic investigations in preclinical disease models to understand the relationship between wild-derived, naturally co-evolved microbiota and mammalian immune responses and metabolism, and how defects in these processes cause diseases. The Staff Scientist will work independently under the supervision of a Principal Investigator and interface with animal care technicians at on- and off-campus facilities for the management and husbandry of mouse colonies with wild-derived microbiota. Specific responsibilities for the Staff Scientist include:

• Conduct and publish research projects in mouse models of inflammation and metabolism
• Maintain and analyze large data bases on microbiota and immune phenotype of mice
• Train postdoctoral fellows and students in methods of basic immunology, flow cytometry and molecular biology research
• Work as a team member within the Immunology Section, Liver Diseases Branch as well as collaborate with other investigators at the NIH.
• Coordinate husbandry, establishment and maintenance of mouse colonies and subcolonies with natural microbiota, and write amendments of the animal study protocol

Applicants must have a Ph.D. in a relevant field. The ideal candidate must have experience with role of wild-derived microbiota in preclinical mouse models of inflammation and metabolism in addition to basic immunology, flow cytometry and molecular biology research, as well as data analysis skills. The position requires good interpersonal skills to facilitate productive professional interactions with postdoctoral fellows and students in the Immunology Section, Liver Diseases Branch, veterinarians, animal facility coordinators and animal care technicians, and internal and external collaborators.

As an NIH employee, you may be entitled to the seven benefit programs (health, dental, vision, flexible spending accounts, life, long term care, and retirement). For more information about these programs and their rates, go to www.opm.gov/insure. DHHS is an equal opportunity employer. The NIH is dedicated to building a diverse community in its training and employment programs. Applications from underrepresented groups and female candidates are particularly encouraged. Salary is dependent on qualifications and experience. A full package of Civil Service benefits is available including retirement, health and life insurance, long-term care insurance, leave and savings plan (401 (k) equivalent). Appointments for this position are made as Staff Scientist and are open to all sources. The position is based in Bethesda, Maryland.