Job
Research Associate- Antibody Discovery
Organization
Meso-Scale Diagnostics, Gaithersburg, Maryland, United States
Scientific focus area
Biomedical Engineering and Biophysics, Structural Biology, Molecular Biology and Biochemistry
Position Summary: The Senior Research Associate in Antibody Discovery is responsible for advancing our antibody discovery programs by supporting and executing various laboratory-based activities, including phage display, antibody production, and downstream characterization.
About the position
Duties and Responsibilities:
- Perform high-throughput screening of antibody libraries using techniques such as phage display.
- Conduct binding and functional assays (e.g., ELISA, flow cytometry, SPR, BLI) to characterize antibody-antigen interactions.
- Express, purify, and analyze antibodies using molecular biology, protein expression, and purification techniques (e.g., PCR, cloning, transient/stable transfection, chromatography).
- Analyze experimental data and present findings to the team.
- Maintain accurate and detailed laboratory records, including experimental procedures, results, and conclusions.
- Contribute to the preparation of technical reports, presentations, and scientific publications.
- Participate in project meetings and contribute to the design and planning of experiments.
- Communicate effectively with team members and external collaborators.
Apply for this vacancy
What you'll need to apply
Please apply online via the MSD Career Website: https://recruiting.ultipro.com/MES1002MESSD/JobBoard/888390fa-f9e8-4b6f-9977-7e3a214369f0/OpportunityDetail?opportunityId=dd53ec72-c186-4770-ad1b-4624e6911314
Contact name
Kathryn Diederichs
Contact email
Qualifications
- Bachelor’s degree in Molecular Biology, Biochemistry, Immunology or related area is required.
- Master’s degree is preferred.
- A minimum of two years of hands-on laboratory experience in antibody discovery or a related field. Industry experience is a plus.
Knowledge, Skills, and Abilities
- Proficiency in molecular biology techniques (e.g., cloning, PCR, site-directed mutagenesis).
- Experience with antibody screening and characterization assays (e.g., ELISA, flow cytometry, SPR, BLI).
- Familiarity with protein expression and purification methods (e.g., mammalian, bacterial, or yeast expression systems).
- Strong analytical and problem-solving skills.
- Demonstrated aptitude for learning of and adhering to standard laboratory techniques and safety precautions.
- Solid communication (written and verbal) skills regardless of the format (e.g., documents, public speaking situations, presentations, etc.).
- Excellent organizational, planning, and time management skills with the ability to manage multiple and often changing priorities and issues of varying complexity, while meeting time-sensitive deadlines and deliverables.
- Attention to detail with demonstrated commitment to excellence and performance.
- Demonstrated propensity to be creative, collaborative, proactive, and self-motivated in the execution and completion of assigned tasks.
- Ability to work both independently and as an effective team member.
- Ability to execute complex experiments with limited guidance.
- Ability to identify issues and troubleshoot solutions.
- Solid data analysis skills. Sound knowledge of MS Excel. Knowledge of GraphPad Prism and SharePoint a plus. Basic knowledge of statistics.
Physical Demands:
- While performing the duties of this job, the individual is frequently required to sit and stand for long periods. The individual is occasionally required to walk; use hands and fingers to operate, handle, or feel objects, tools, or controls; reach with hands and arms.
- Up to 75% of the day may be spent at a lab bench.
- There are aspects of the position’s duties that require a person in this role to work at heights above four (4) feet on occasion and move/lift up to 25 pounds.
Work Environment:
- Laboratory environment working with chemical reagents and performing some Biosafety Level 2 work.
- May involve handling of BSL-2 materials and organisms including human blood and/or blood products.
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