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Job

Postdoctoral Fellow - Computational Biology

Organization

Fralin Biomedical Research Institute DC of Virginia Tech, Washington, District of Columbia, United States

Scientific focus area

Cancer Biology, Genetics and Genomics, Immunology, Computational Biology

Dr. Shenglin Mei lab at Fralin Biomedical Research Institute (FBRI) Cancer Research Center DC of Virginia Tech and Children's National Center for Cancer and Immunology Research, is seeking highly motivated Computational Biology postdoctoral fellow to join our team.

About the position

The Mei Laboratory (https://shenglinmei.github.io/ ) studies the remodeling and regulatory mechanisms of the tumor microenvironment during tumor progression and metastasis. The lab combines single-cell technologies, genomic datasets, machine learning, and experimental methods to investigate how the tumor microenvironment and gene regulatory factors control tumor metastasis cascade. By advancing our understanding of malignant cell heterogeneity and tumor microenvironment remodeling, we aim to drive the development of novel therapeutic approaches for patients with metastatic cancer.

The current focuses in lab include the following directions:

  1. Developing computational methods for integrating multi-modal data, such as scRNA-seq, scATAC-seq, spatial transcriptomics, ChIP-seq, and CRISPR screening.
  2. Investigating context-dependent remodeling of the tumor microenvironment.
  3. Identifying novel regulators within the tumor microenvironment.
  4. Exploring tumor organ specific metastasis with multi-omics data integration.

The successful candidates will collaborate with researchers across multiple institutions. Our lab is primarily affiliated with the Fralin Biomedical Research Institute (FBRI) Cancer Research Center DC of Virginia Tech and jointly we are members of the Children's National Center for Cancer and Immunology Research.

The positions offer annual salary of $65,000~$70,000 and are adjustable based on research experience.

Apply for this vacancy

What you'll need to apply

Interested applicants should submit the following materials via email to Dr. Shenglin Mei (shenglinmei@vtc.vt.edu):

  1. A cover letter describing current research activities and your interest in this position
  2. a current CV (including publications), and
  3. contact information for three references.

Contact name

Shenglin Mei

Contact email

shenglinmei@vtc.vt.edu

Qualifications

Required qualifications:

  • PhD and/or MD in Computational Biology, Bioinformatics, Genomics, Biology, Data Science, Computer science or other related fields.
  • Experience in high-throughput sequencing data analysis.
  • Track record of first/co-first-author original research papers.
  • Strong programming skills in Python or R, and Linux Shell.
  • Creative, independent, and highly motivated, with good communication skills.

Preferred qualifications:

  • Experience in developing algorithms for analysis of biological data.
  • Experience with single cell and spatial transcriptome data analysis.
  • Experience in supervised and unsupervised machine learning, or deep learning models.

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