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Job

Postdoctoral position at the NCI

A postdoctoral position is available at the DNA Replication Group (PI: Mirit I. Aladjem, Ph.D.), a part of the NCI’s Developmental Therapeutics Branch in Bethesda, Maryland. Our group aims to understand cellular networks that signal to and from chromatin to modulate DNA replication. Since many regulatory feedback pathways are deregulated in cancer cells, the results of these studies will help our understanding of cancer biology and the mechanisms underlying therapeutic strategies.

About the position

The project builds on our recent comprehensive analyses of distinct protein-DNA interactions associated with human replication origins, shown to modulate the progress of DNA replication. Our research strategy combines sequencing-based analyses with single-fiber studies to identify specific replication and repair pathways that affect the pace and frequency of DNA replication. We use these tools to ask how the molecular interactions that affect DNA replication respond to environmental challenges and how modulation of these responses affect the sensitivity of malignant cells to anti-cancer therapy. Training opportunities are augmented by collaborations with colleagues, physicians and pharmacologists from the intramural and extramural communities. Fellows are encouraged to take advantage of formal, focused courses (e.g. training in bioinformatics and translational research), actively engage in mentoring and participate in a variety of community activities including the NIH’s cell cycle interest group, DNA repair interest group and the NCI's Center of Excellence in Chromosome Biology. For more details, please see https://ccr.cancer.gov/staff-directory/mirit-i-aladjem

Apply for this vacancy

What you'll need to apply

To apply, please send a current CV, a statement of interest and names of 3 colleagues who are willing to provide reference letters to:

Mirit I. Aladjem, Ph.D. Senior Investigator Head,
DNA Replication Group, Deputy Chief,
Developmental Therapeutics Branch Center for Cancer Research,
NCI, NIH aladjemm@mail.nih.gov

Contact name

Dr. Mirit I Aladjem

Contact email

aladjemm@mail.nih.gov

Apply now

Disclaimer/Fine Print

Selection for this position will be based solely on merit, with no discrimination for non-merit reasons such as race, color, religion, gender, sexual orientation, national origin, political affiliation, marital status, disability, age, or membership or non-membership in an employee organization. The NIH encourages the application and nomination of qualified women, minorities, and individuals with disabilities.

This postdoc fellowship opportunity at NIH is covered by a bargaining unit, the UAW Local 2750 also known as the NIH Fellows United.